非click反应高效构建三氮唑三氮唑结构广泛见于药物分子和天然产物中，构建该结构的最经典方法莫过于点击化学的方法，也就是铜催化叠氮类化合物和炔的高效Click反应。来自美国Rib-X Pharmaceuticals, Inc....有机方法2020-05-163.5W
Boron-Catalyzed O-H Bond Insertion of α-Aryl α-Diazoesters in WaterA catalytic, metal-free O-H bond insertion of α-diazoesters in water in the presence of B(C6F5 3·nH2...有机方法2019-08-103.9W
Preparation of 5-Aryl-2-Alkyltetrazoles with Aromatic AldehydesA variety of 5-aryl-2-methyltetrazoles and 5-aryl-2-benzyltetrazoles were directly prepared in goo...有机方法2019-07-154.0W #tetrazole
Chan-Evans-Lam Amination of Boronic Acid Pinacol (BPin) Esters: Overcoming the Aryl Amine ProblemThe Chan-Evans-Lam reaction is a valuable C-N bond forming process. However, aryl boronic acid pin...有机方法2019-07-155.8W #Chan–Lam #Pinacol #Amination
Highly Discriminative and Chemoselective DeprotectionAcetals are the most useful protecting groups for carbonyl functional groups. In addition to the r...有机方法2019-06-294.1W
Systematic Evaluation of 2-Arylazocarboxylates and 2-Arylazocarboxamides as Mitsunobu Reagents2-Arylazocarboxylate and 2-arylazocarboxamide derivatives can serve as replacements of typical Mit...有机方法2019-05-034.0W
Synthesis of Nitroolefins and Nitroarenes under Mild Conditions1,3-Disulfonic acid imidazolium nitrate {[Dsim]NO3} was prepared and characterized as a new ionic...有机方法2019-04-153.6W
MIDA Boronates(Burke硼酸酯)Burke硼酸酯可起到与B-保护的卤硼酸一样的作用而用于各种多重交叉偶联反应。使用温和的水相NaOH、NaHCO3为碱时可释放出相应的硼酸。Burke硼酸酯可兼容许多合成试剂，能用于将简单的含硼起始原...有机方法2019-04-066.3W
一种实用的还原胺化还原剂2-甲基吡啶硼烷醛(酮 一锅还原胺化是有机化学中的一个重要反应，常用的还原剂有NaBH3CN、NaBH(OAc 3、吡啶硼烷络合物等。文献中有报道吡啶硼烷络合物环境友好，可以避免NaBH3CN在产品或后处理中产生氰化...有机方法2019-04-056.3W
Amination of Arylboronic Compounds via the Copper-Catalyzed Addition of Arylboronic Esters Arylboronic esters add to di-tert-butyl azodicarboxylate under mild reaction conditions (at room t...有机方法2019-02-184.3W
Desulfonylative Methenylation of β-Keto SulfonesA one-step strategy for the synthesis of α-methenyl ketones from β-keto sufones is reported. Succe...有机方法2019-01-053.7W
Cy*Phine Ligand for Efficient Cross-Coupling Common namePd(Cy*Phine 2Cl2Assay95%CAS #1668598-24-0Molecular FormulaC78H106Cl2P2PdMolecular Weight1...有机方法2018-11-055.9W #Sonogashira
