Copper-Catalyzed Synthesis of Substituted Benzothiazoles

An efficient and convenient method was developed for the formation of 2-substituted benzothiazoles via a copper-catalyzed condensation of 2-aminobenzenethiols with nitriles. The developed method is applicable to a wide range of nitriles containing different functional groups furnishing excellent yields of the corresponding products.

https://pubs.acs.org/doi/abs/10.1021/ol400379z

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