Chemoselective Suzuki Coupling of Diborylmethane for Facile Synthesis of Benzylboronates

The chemoselective Pd-catalyzed Suzuki–Miyaura cross-coupling reaction using a diborylmethane is reported. The use of an equimolar amount of base with a diborylmethane realized chemoselective coupling for the synthesis of various benzylboronate derivatives. Sterically hindered aryl bromides can give products in moderate to excellent yields.

https://pubs.acs.org/doi/abs/10.1021/ol201115k

标签： benzylboronates